According to Bet365, Iga Swiatek, Aryna Sabalenka, Coco Gauff and Mirra Andreeva are the top favorites to conquer the tournament in the U.S. Open.

Top favorites

• Iga Swiatek 3.50
• Aryna Sabalenka 3.50
• Coco Gauff 7.50
• Mirra Andreeva 10.00
• Elena Rybakina 13.00
• Naomi Osaka 15.00
• Emma Raducanu 21.00
• Amanda Anisimova 21.00
• Jessica Pegula 29.00
• Barbora Krejcikova 41.00
• Jasmine Paolini 51.00
• Karolina Muchova 67.00
• Danielle Collins 67.00
• Belinda Bencic 67.00
• Anke Huber
• Anke Huber

Iga Swiatek in 2025

Currently the world no.2, Swiatek played her last match on the 18^th of August when she defeated world no.8 Jasmine Paolini 7-5 6-4 in the final in Cincinnati to win her 25^th career title.

At the moment, during this season the Pole owns a compiled 49-12 win-loss record. Swiatek clinched 2 titles in 2025 in Wimbledon and Cincinnati. The Pole reached the final in Australia and Bad Homburg.

Iga Swiatek will come up against the world no.84 Emiliana Arango in the 1^st round on Tuesday at 11:30 am on Arthur Ashe Stadium. In the past, they have never played each other so far in top competitions.

The Pole clinched 2 titles in 2025 in Wimbledon and Cincinnati. The Pole reached the final in Australia (United Cup) and in Bad Homburg (Bad Homburg Open).

Iga won 25 titles in her career: 14 on hard courts, 10 on clay courts and 1 on grass courts. (See the list of her titles)

Aryna Sabalenka in 2025

Currently the world no.1, Sabalenka played her last match on the 24^th of August when she overcame world no.108 Rebeka Masarova 7-5 6-1 in the 1^st round of the U.S. Open (draw).

Currently, during this year the Belarussian owns an overall 51-10 match record. The Belarussian clinched 3 titles in 2025 in Brisbane, Miami and Madrid. Aryna was the finalist at the Australian Open, Indian Wells, Stuttgart and French Open.

Aryna Sabalenka will take on the world no.67 Polina Kudermetova in the 2^nd round. Their head to head is 1-0 for Sabalenka.

Sabalenka has won 3 titles in 2025 in Brisbane, Miami and Madrid. Aryna was the runner-up at the Australian Open, in Indian Wells (BNP Paribas Open), in Stuttgart (Porsche Tennis Grand Prix) and at the French Open.

The Belarussian won 20 titles in her career: 15 on hard courts, 3 on clay courts and 2 on indoor courts. (See the list of her titles)

Coco Gauff in 2025

Now ranked no.3, the American played her last match on the 15^th

of August when she surrendered to world no.8 Jasmine Paolini 2-6 6-4 6-3 in the quarter in Cincinnati (draw).

Currently, during this season the American has achieved an overall 35-12 record. Coco has won 2 titles in 2025 in Australia and French Open. Coco got to the final in Madrid and Rome.

Coco Gauff will take on the world no.79 Ajla Tomljanovic in the 1^st round on Tuesday at 7:00 pm on Arthur Ashe Stadium. Their current record is 1-0 for Gauff.

Gauff conquered 2 titles in 2025 in Australia and French Open. Coco was the finalist in Madrid (Mutua Madrid Open) and in Rome (Internazionali BNL d’Italia).

The American won 11 titles in her career: 7 on hard courts, 2 on clay courts and 2 on indoor courts. (See the list of her titles)

Mirra Andreeva in 2025

Currently the world no.5 (career-high), the Russian played her last match on the 25^th of August when she overcame world no.56 Alycia Parks 6-0 6-1 in the 1^st round of the U.S. Open (draw).

At the moment, during this season Andreeva owns a compiled 37-12 win-loss record. The Russian conquered 2 titles in 2025 in Dubai and Indian Wells.

Mirra Andreeva will play the world no.53 Anastasia Potapova in the 2^nd round. Their current record is 1-1.

Mirra conquered 2 titles in 2025 in Dubai and Indian Wells.