Stefanos Tsitsipas and Alexandre Muller will fight against each other in the 1st round of the U.S. Open for the 3rd time in their career. They are scheduled to compete on Tuesday at 4:00 pm on Court 7. In the following paragraphs, you can find the head to head analysis and prediction.
Prediction, odds and live streaming
The pick for Tennis Tonic is Stefanos Tsitsipas who should win in 5 sets.
As per the initial odds, Stefanos Tsitsipas is the pick to win this match.
Stefanos Tsitsipas -> 1.56
Alexandre Muller -> 2.43
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Prediction and head to head Stefanos Tsitsipas vs. Alexandre Muller
This will be the 3rd time that Stefanos Tsitsipas and Alexandre Muller face off. The head to head is 2-0 for Tsitsipas (see full H2H stats), 1-0 on hard.
The last time that they competed against each other, Tsitsipas won 6-2 7-6(3) in the 2nd round in Rome back in May 2025.
Highlights Stefanos Tsitsipas vs Alexandre Muller – Rome 09-May-2025
Stefanos Tsitsipas
20 - 16win/loss
34
3
LWLWLLWLLL | Year | Total | Hard | Clay | I.hard | Grass | Carpet |
|---|---|---|---|---|---|---|
| 2025 | 22-18 | 12-10 | 7-5 | 2-1 | 1-2 | 0-0 |
| 2024 | 45-22 | 13-11 | 22-6 | 8-3 | 2-2 | 0-0 |
| 2023 | 51-24 | 19-9 | 17-5 | 11-6 | 4-4 | 0-0 |
| 2022 | 61-24 | 18-8 | 17-4 | 18-9 | 8-3 | 0-0 |
| 2021 | 55-19 | 26-8 | 23-5 | 6-5 | 0-1 | 0-0 |
Ranked no. 28, Tsitsipas will start his run at the U.S. Open after he played his last match in Winston Salem where he lost 6-3 6-2 to Yunchaokete in the 2nd round on the 19th of August.
Stefanos has a composed 20-16 win-loss record in 2025, 10-8 on hard (See FULL STATS).
His best result of the current season was winning the title in Dubai where he defeated Felix Auger-Aliassime in the final 6-3 6-3.
Talking about his overall career, Tsitsipas has an overall 509-241 record. He has a positive 191-104 record on hard.
Previously at the U.S. Open
Previously, his best result was reaching the 3rd round in 2020 and 2021. See his history.
Alexandre Muller
22 - 22win/loss
42
38
LWWLWLLLLW | Year | Total | Hard | Clay | I.hard | Grass | Carpet |
|---|---|---|---|---|---|---|
| 2025 | 26-29 | 12-12 | 11-10 | 3-4 | 0-3 | 0-0 |
| 2024 | 35-32 | 11-14 | 20-12 | 3-5 | 1-1 | 0-0 |
| 2023 | 46-33 | 20-13 | 18-12 | 7-7 | 1-1 | 0-0 |
| 2022 | 38-31 | 6-6 | 27-20 | 4-4 | 1-1 | 0-0 |
| 2021 | 27-31 | 6-7 | 16-15 | 5-7 | 0-2 | 0-0 |
Ranked no. 38 (career-high), the French player will start his run at the New York after he played his last match in Winston Salem where he lost 6-3 6-2 to Mpetshi in the 3rd round on the 20th of August.
Muller has an overall 22-22 win-loss record in 2025, 11-9 on hard (See FULL STATS).
His best result of the current season was winning the title in Hong Kong where he defeated Kei Nishikori in the final 2-6 6-1 6-3.
In terms of his career, The French player has an overall 420-293 record. He has a positive 131-85 record on hard.
Previously at the U.S. Open
Previously, his best result was reaching the 2nd round in 2024. See his history.
Head 2 Head
LWLWLLWLLL
LWWLWLLLLW Tennis Scores – U.S. Open
- Taylor FritzFritz – Emilio NavaNava (7-5 6-2 6-3) – Stats, scores, rankings
- Ugo BlanchetBlanchet – Fabian MarozsanMarozsan (6-4 3-6 7-67 6-2) – Stats, scores, rankings
- Marcos GironGiron – Mariano NavoneNavone (6-0 7-5 4-6 5-7 6-4) – Stats, scores, rankings
- Pablo Carreno-BustaCarreno-Busta – Pablo Llamas RuizLlamas Ruiz (7-67 6-4 6-2) – Stats, scores, rankings
- Tomas MachacMachac – Luca NardiNardi (6-3 6-1 6-1) – Stats, scores, rankings
- Luciano DarderiDarderi – Rinky HijikataHijikata (6-2 6-1 6-2) – Stats, scores, rankings
- Novak DjokovicDjokovic – Learner TienTien (6-1 7-63 6-2) – Stats, scores, rankings
- Zachary SvajdaSvajda – Zsombor PirosPiros (6-4 6-2 7-5) – Stats, scores, rankings
- Ben SheltonShelton – Ignacio BuseBuse (6-3 6-2 6-4) – Stats, scores, rankings
- Adrian MannarinoMannarino – Tallon GriekspoorGriekspoor (7-5 6-4 6-0) – Stats, scores, rankings
- Tomas Martin EtcheverryMartin Etcheverry – Camilo Ugo CarabelliUgo Carabelli (6-3 6-2 6-0) – Stats, scores, rankings
- Jakub MensikMensik – Nicolas JarryJarry (7-65 6-3 6-4) – Stats, scores, rankings
- Benjamin BonziBonzi – Daniil MedvedevMedvedev (6-3 7-5 6-75 0-6 6-4) – Stats, scores, rankings
- Arthur RinderknechRinderknech – Roberto Carballes BaenaCarballes Baena (7-62 7-5 4-6 6-2) – Stats, scores, rankings
- Brandon NakashimaNakashima – Jesper De JongDe Jong (6-2 6-75 2-6 6-2 7-67) – Stats, scores, rankings
- Eliot SpizzirriSpizzirri – Stefan DostanicDostanic (7-5 6-4 7-64) – Stats, scores, rankings
- Jordan ThompsonThompson – Corentin MoutetMoutet (6-2 6-4 1-6 6-3) – Stats, scores, rankings
- Jerome KymKym – Ethan QuinnQuinn (6-3 6-2 3-6 7-65) – Stats, scores, rankings
- Jiri LeheckaLehecka – Borna CoricCoric (3-6 6-4 7-65 6-1) – Stats, scores, rankings
- Alejandro Davidovich FokinaDavidovich Fokina – Alexander ShevchenkoShevchenko (6-1 6-1 6-2) – Stats, scores, rankings
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