According to Bet365, Jannik Sinner, Carlos Alcaraz, Novak Djokovic and Jack Draper are the top favorites to conquer the tournament in the U.S. Open.

Top favorites

• Jannik Sinner 2.10
• Carlos Alcaraz 2.62
• Novak Djokovic 13.00
• Jack Draper 19.00
• Alexander Zverev 21.00
• Ben Shelton 21.00
• Taylor Fritz 29.00
• Daniil Medvedev 51.00
• Holger Rune 67.00
• Alex De Minaur 67.00
• Stefanos Tsitsipas 81.00
• Frances Tiafoe 101.00
• Andrey Rublev 101.00
• Tommy Paul 101.00
• Lorenzo Musetti 101.00
• Jakub Mensik 101.00
• Gustavo Kuerten
• Gustavo Kuerten

Jannik Sinner in 2025

Ranked no.1, the Italian played his last match on the 18^th of August when he had to retire when playing against world no.2 Carlos Alcaraz in the final and the scoreline was 5-0 .

Until now, during this year the Italian has achieved an overall 31-4 match record. Jannik has won 2 titles in 2025 at the Australian Open and Wimbledon. Jannik was the finalist in Rome, French Open and Cincinnati.

Jannik Sinner will take on the world no.87 Vit Kopriva in the 1^st round. In the past, they have never competed against each other so far on the main tour.

Sinner has won 2 titles in 2025 at the Australian Open and Wimbledon. The Italian was the runner-up in Rome (Internazionali BNL d’Italia), at the French Open and in Cincinnati (Cincinnati Open).

Jannik won 21 titles in his career: 10 on hard courts, 1 on clay courts, 8 on indoor courts and 2 on grass courts. (See the list of his titles)

Carlos Alcaraz in 2025

Ranked world no.2, Alcaraz played his last match on the 18^th of August when he overcame world no.1 Jannik Sinner 5-0 in the final in Cincinnati to win his 23^rd career title.

This year Alcaraz achieved an overall 54-6 match record. Carlos conquered 6 titles in 2025 in Rotterdam, Monte-Carlo, Rome, French Open, London and Cincinnati. Carlos was the runner-up in Barcelona and Wimbledon.

Carlos Alcaraz will come up against the world no.66 Reilly Opelka in the 1^st round. They have never competed against each other till now in top tournaments.

Alcaraz clinched 6 titles in 2025 in Rotterdam, Monte-Carlo, Rome, French Open, London and Cincinnati. Alcaraz was the finalist in Barcelona (Barcelona Open Banc Sabadell) and in Wimbledon.

Carlos won 23 titles in his career: 6 on hard courts, 11 on clay courts, 2 on indoor courts and 4 on grass courts. (See the list of his titles)

Novak Djokovic in 2025

Currently ranked no.7, the Serbian played his last match on the 11^th

of July when he was overcome by world no.1 Jannik Sinner 6-3 6-3 6-4 in the semifinal in Wimbledon (draw).

This year Novak has achieved a composed 26-9 match record. The Serbian clinched 1 title in Geneva. The Serbian was the runner-up in Miami.

Novak Djokovic will compete against the world no.48 Learner Tien in the 1^st round. In the past, they have never played each other as of now in top competitions.

The Serbian clinched 1 title in 2025 in Geneva. The Serbian reached the final in Miami (Miami Open).

The Serbian won 100 titles in his career: 52 on hard courts, 21 on clay courts, 19 on indoor courts and 8 on grass courts. (See the list of his titles)

Jack Draper in 2025

At the moment ranked no.5, Jack played his last match on the 3^rd of July when he lost to world no.61 Marin Cilic 6-4 6-3 1-6 6-4 in the 2^nd round in Wimbledon (draw).

Until now, during this year Jack has managed to achieve an overall 29-9 match record. This year, Jack clinched 1 title in Indian Wells. The Brit was the finalist in Doha and Madrid.

The Brit has won 1 title in 2025 in Indian Wells. Jack was the runner-up in Doha (Qatar ExxonMobil Open) and in Madrid (Mutua Madrid Open).