Stefanos Tsitsipas and John Isner will face off in the 2nd round of the Abierto de Tenis Mifel for the 8th time in their career. They are scheduled to play on Wednesday at 9:00 pm on ESTADIO MEXTENIS. In this post, we analyze their head to head performance and prediction.

Prediction, odds and live streaming

The pick for Tennis Tonic is Stefanos Tsitsipas who should win in 2 sets.

As per the initial odds, Stefanos Tsitsipas is the pick to win this match.
Stefanos Tsitsipas -> 1.3
John Isner -> 3.52

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Prediction and head to head Stefanos Tsitsipas vs. John Isner

This will be the 8th time that Stefanos Tsitsipas and John Isner fight against each other. The head to head is 5-2 for Tsitsipas (see full H2H stats), 4-1 on hard.

The last time that they competed against each other, Tsitsipas won 7-6(5) 5-7 6-3 in the quarter in Cincinnati back in 2022.

Highlights Stefanos Tsitsipas vs John Isner – Cincinnati 19-August-2022

Stefanos Tsitsipas

Stefanos Tsitsipas

0 - 0win/loss

Rank
34
High
3
LWLWLLWLLL
Year Total Hard Clay I.hard Grass Carpet
2025 22-18 12-10 7-5 2-1 1-2 0-0
2024 45-22 13-11 22-6 8-3 2-2 0-0
2023 51-24 19-9 17-5 11-6 4-4 0-0
2022 61-24 18-8 17-4 18-9 8-3 0-0
2021 55-19 26-8 23-5 6-5 0-1 0-0

Ranked no. 5, the Greek will start his run in Los Cabos after he played his last match at Wimbledon where he lost 3-6 7-6(4) 3-6 6-4 6-4 to Eubanks in the 4th round on the 10th of July.

Tsitsipas has a composed 35-13 win-loss record in 2023, 11-3 on hard (See FULL STATS).

Tsitsipas’s best result of the season was reaching the final at the Australian Open and Barcelona.

Talking about his overall career, Tsitsipas has an overall 428-192 record. He has a positive 160-79 record on hard.

Previously in Los Cabos

The Greek has never competed in this tournament before.

Los Cabos
Tsitsipas's Record

John Isner

John Isner

8 - 12win/loss

Hard
1-7
I Hard
4-1
Clay
0-2
Grass
3-2
Rank
172
High
8
LWLLWLLWWW
Year Total Hard Clay I.hard Grass Carpet
2023 9-14 2-9 0-2 4-1 3-2 0-0
2022 23-17 9-9 7-4 3-2 4-2 0-0
2021 23-13 18-7 5-2 0-3 0-1 0-0
2020 10-10 9-8 1-1 0-1 0-0 0-0
2019 30-18 22-14 0-0 3-3 5-1 0-0

Ranked no. 114, John got to the 2nd round after defeating Rinky Hijikata 6-2 7-64.

In the 1st round, Isner had a good straight sets win against Hijikata (6-2 7-64). During the match Isner scored 80 points vs Hijikata’s 63. Isner was extremely aggressive to blast 34 winners.

Talking about serving, Isner bagged 19 aces and he committed only 2 double faults. Overall, John Isner was quite effective on serve to win 76% (34/45) of his 1st serve and 58% (11/19) on the second serve. However, this didn’t prevent his to concede the serve once. The American broke Hijikata 3 times after converting 25% of his break points (3/12).

The American’s best result of the current season was getting to the final Dallas.

Isner has an aggregate 8-11 win-loss record in 2023, 1-6 on hard (See FULL STATS).

Los Cabos
Isner's Record

Tennis Scores in Los Cabos

Upcoming matches in the draw