
Stefanos Tsitsipas and John Isner will face off in the 2nd round of the Abierto de Tenis Mifel for the 8th time in their career. They are scheduled to play on Wednesday at 9:00 pm on ESTADIO MEXTENIS. In this post, we analyze their head to head performance and prediction.
Prediction, odds and live streaming
The pick for Tennis Tonic is Stefanos Tsitsipas who should win in 2 sets.
As per the initial odds, Stefanos Tsitsipas is the pick to win this match.
Stefanos Tsitsipas -> 1.3
John Isner -> 3.52
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Prediction and head to head Stefanos Tsitsipas vs. John Isner
This will be the 8th time that Stefanos Tsitsipas and John Isner fight against each other. The head to head is 5-2 for Tsitsipas (see full H2H stats), 4-1 on hard.
The last time that they competed against each other, Tsitsipas won 7-6(5) 5-7 6-3 in the quarter in Cincinnati back in 2022.
Highlights Stefanos Tsitsipas vs John Isner – Cincinnati 19-August-2022
Stefanos Tsitsipas
Year | Total | Hard | Clay | I.hard | Grass | Carpet |
---|---|---|---|---|---|---|
2025 | 16-9 | 9-5 | 5-3 | 2-1 | 0-0 | 0-0 |
2024 | 45-22 | 13-11 | 22-6 | 8-3 | 2-2 | 0-0 |
2023 | 51-24 | 19-9 | 17-5 | 11-6 | 4-4 | 0-0 |
2022 | 61-24 | 18-8 | 17-4 | 18-9 | 8-3 | 0-0 |
2021 | 55-19 | 26-8 | 23-5 | 6-5 | 0-1 | 0-0 |
Ranked no. 5, the Greek will start his run in Los Cabos after he played his last match at Wimbledon where he lost 3-6 7-6(4) 3-6 6-4 6-4 to Eubanks in the 4th round on the 10th of July.
Tsitsipas has a composed 35-13 win-loss record in 2023, 11-3 on hard (See FULL STATS).
Tsitsipas’s best result of the season was reaching the final at the Australian Open and Barcelona.
Talking about his overall career, Tsitsipas has an overall 428-192 record. He has a positive 160-79 record on hard.
Previously in Los Cabos
The Greek has never competed in this tournament before.
John Isner


8 - 12win/loss
172
8

Year | Total | Hard | Clay | I.hard | Grass | Carpet |
---|---|---|---|---|---|---|
2023 | 9-14 | 2-9 | 0-2 | 4-1 | 3-2 | 0-0 |
2022 | 23-17 | 9-9 | 7-4 | 3-2 | 4-2 | 0-0 |
2021 | 23-13 | 18-7 | 5-2 | 0-3 | 0-1 | 0-0 |
2020 | 10-10 | 9-8 | 1-1 | 0-1 | 0-0 | 0-0 |
2019 | 30-18 | 22-14 | 0-0 | 3-3 | 5-1 | 0-0 |
Ranked no. 114, John got to the 2nd round after defeating Rinky Hijikata 6-2 7-64.
In the 1st round, Isner had a good straight sets win against Hijikata (6-2 7-64). During the match Isner scored 80 points vs Hijikata’s 63. Isner was extremely aggressive to blast 34 winners.
Talking about serving, Isner bagged 19 aces and he committed only 2 double faults. Overall, John Isner was quite effective on serve to win 76% (34/45) of his 1st serve and 58% (11/19) on the second serve. However, this didn’t prevent his to concede the serve once. The American broke Hijikata 3 times after converting 25% of his break points (3/12).
The American’s best result of the current season was getting to the final Dallas.
Isner has an aggregate 8-11 win-loss record in 2023, 1-6 on hard (See FULL STATS).
Head 2 Head



Tennis Scores in Los Cabos
- Nicolas JarryJarry – Rodrigo Pacheco MendezPacheco Mendez (6-3 6-1) – See score progression
- Dominik KoepferKoepfer – Tomas Barrios VeraBarrios Vera (6-4 6-3) – See score progression
- Jason JungJung – Ernesto EscobedoEscobedo (3-6 7-65 6-2) – See score progression
- James DuckworthDuckworth – Otto VirtanenVirtanen (6-3 6-0) – See score progression
- Alex De MinaurDe Minaur – Skander MansouriMansouri (6-4 6-4) – See score progression
- Felipe Meligeni AlvesMeligeni Alves – Alejandro TabiloTabilo (6-2 6-4) – See score progression
- Gijs BrouwerBrouwer – Gabriel DialloDiallo (6-2 4-6 6-2) – See score progression
- John IsnerIsner – Rinky HijikataHijikata (6-2 7-64) – See score progression
- Thiago Agustin TiranteAgustin Tirante – Gonzalo LamaLama (7-63 6-2) – See score progression
- Aleksandar KovacevicKovacevic – Omni KumarKumar (6-2 7-5) – See score progression
- Nicolas JarryJarry – Rodrigo Pacheco MendezPacheco Mendez (6-3 6-1) – See score progression
- Jason JungJung – Ernesto EscobedoEscobedo (3-6 7-6(5) 6-2) – See score progression
- Alex De MinaurDe Minaur – Skander MansouriMansouri (6-4 6-4) – See score progression
- Dominik KoepferKoepfer – Tomas Barrios VeraBarrios Vera (6-4 6-3) – See score progression
- James DuckworthDuckworth – Otto VirtanenVirtanen (6-3 6-0) – See score progression
Upcoming matches in the draw
- Borna CoricCoric – Jason JungJung (0-0) – H2H and prediction
- Stefanos TsitsipasTsitsipas – John IsnerIsner (5-2) – H2H and prediction
- Borna GojoGojo – Christian GarinGarin (0-0) – H2H and prediction
- Gijs BrouwerBrouwer – Nicolas JarryJarry (0-0) – H2H and prediction
- Dominik KoepferKoepfer – James DuckworthDuckworth (0-1) – H2H and prediction
- Felipe Meligeni Rodrigues AlvesMeligeni Rodrigues Alves – Tommy PaulPaul (0-0) – H2H and prediction
- Aleksandar KovacevicKovacevic – Cameron NorrieNorrie (0-0) – H2H and prediction
- Alex De MinaurDe Minaur – Thiago Agustin TiranteAgustin Tirante (0-0) – H2H and prediction
- Beibit ZhukayevZhukayev – Ilya IvashkaIvashka (0-0) – H2H and prediction