H2H, PREDICTION Rafael Nadal vs John Isner | Rome odds, preview, pick

PREVIEW. Rome. Nadal and Isner will face off in the 2nd round of the Internazionali BNL d'Italia. See the prediction, H2H stats, odds, and preview of their next match

Prediction and head to head Rafael Nadal vs. John Isner

Rafael Nadal and John Isner will square off in the 2nd round of the Internazionali BNL d’Italia for the 9th time in their career. They are scheduled to play on Wednesday at 1:30 pm on CENTER COURT. In the following lines you can find the head to head analysis and prediction.

Prediction, odds and live streaming

The pick for Tennis Tonic is Rafael Nadal who should win in 2 sets.

See updated oddsAs per the initial odds, Rafael Nadal is the pick to win this match.
Rafael Nadal -> 1.14
John Isner -> 6.05

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Prediction and head to head Rafael Nadal vs. John Isner

This will be the 9th time that Rafael Nadal and John Isner fight against each other. The head to head is 7-1 for Nadal (see full H2H stats), 4-0 on clay.

The last time that they competed against each other, Nadal won 6-4 7-6(0) in the quarter in Beijing back in 2017.

Rafael Nadal

Rafael Nadal
Rafael Nadal

0 - 0win/loss

Rank
153
High
1
LLWLWWWWLL
Year Total Hard Clay I.hard Grass Carpet
2024 12-8 2-1 10-6 0-1 0-0 0-0
2023 1-3 1-3 0-0 0-0 0-0 0-0
2022 39-8 23-3 10-2 1-3 5-0 0-0
2021 24-5 5-2 19-3 0-0 0-0 0-0
2020 27-7 13-3 9-1 5-3 0-0 0-0

Ranked no. 4, the Spaniard will start his run in Rome after he played his last match in Madrid where he lost 6-2 1-6 6-3 to Alcaraz in the quarter on the 6th of May.

Nadal has an aggregate 22-2 win-loss record in 2022, 2-1 on clay (See FULL STATS).

His best result of the current year was winning the title in in Melbourne where he overcame Maxime Cressy in the final 7-6(6) 6-3 and in at the Australian Open where he overcame Daniil Medvedev in the final 2-6 6-7(5) 6-4 6-4 7-5 and in in Acapulco where he beat Cameron Norrie in the final 6-4 6-4.

Talking about his overall career, Nadal has an overall 1089-221 record. He has a positive 483-45 record on clay.

Previously in Rome

Previously, he won this tournament 10 times in 2005, 2006, 2007, 2009, 2010, 2012, 2013, 2018, 2019 and 2021. See his history.

Nadal
Rome
Nadal's Record

John Isner

John Isner
John Isner

0 - 0win/loss

Rank
172
High
8
LWLLWLLWWW
Year Total Hard Clay I.hard Grass Carpet
2023 9-14 2-9 0-2 4-1 3-2 0-0
2022 23-17 9-9 7-4 3-2 4-2 0-0
2021 23-13 18-7 5-2 0-3 0-1 0-0
2020 10-10 9-8 1-1 0-1 0-0 0-0
2019 30-18 22-14 0-0 3-3 5-1 0-0

Ranked no. 27, John reached the 2nd round after defeating Francisco Cerundolo 6-4 6-3.

In the 1st round, The American had a good straight sets win against Cerundolo (6-4 6-3). During the match Isner scored 69 points vs Cerundolo’s 59. John was very aggressive to blast 30 winners.

About the serving games, Isner scored 13 aces and he was pretty steady in conceding no double faults for the entire match. Overall, John Isner was extremely effective on serve to win 71% (30/42) of his 1st serve and 57% (16/28) on the second serve. However, this didn’t prevent his to concede the serve once. Isner broke Cerundolo 3 times after converting 60% of his break points (3/5).

Isner’s best result of the season was reaching the final in Houston.

John has a compiled 11-10 win-loss record in 2022, 5-2 on clay (See FULL STATS).

Previously in Rome

Previously, his best result was reaching the semifinal in 2017. See his history.

Isner
Rome
Isner's Record
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Head 2 Head

Win Loss
Nadal
Isner
2025 2024 2023
0 - 0
0 - 0

Tennis Scores in Rome

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